IndraLab

Statements


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"As evidence showed that another sulfonylurea drug glipizide also inhibited Sur1 containing K ATP channels but failed to inhibit NLRP3 inflammasome activation."

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"The specific effect of glyburide was confirmed by showing that glipizide, which is structurally similar to glyburide but does not inhibit NLRP3, did not affect the ability of M. tuberculosis to induce IL-1beta production (XREF_FIG) or necrosis (data not shown)."