IndraLab

Statements

UCHL1 binds UCHL3. 6 / 6
| 6
sparser
"To identify the proteins that interact with UCH-L1 or UCH-L3, which might represent the potential substrates or the functional effecters, we performed immunoaffinity chromatography."
19154770
sparser
"In addition, the increased levels of both UCH-L1 and UCH-L3 mRNA are associated with early tumor recurrence of invasive breast cancer and poor prognosis [55] ."
20302916
sparser
"Nedd8, an Ub-like protein with 57% identity to Ub, is a previously reported UCH-L3 and UCH-L1 interacting protein ( Wada et al., 1998; Hemelaar et al., 2004 )."
19154770
sparser
"Thus, the interactions of di-Ub with UCH-L3 and mono-Ub with UCH-L1 occupy the catalytic centers of UCH-L3, and UCH-L1, respectively."
19154770
sparser
"This resulted in UCHL3:UCHL1 selectivity for UbV Q40V/T66K/V70F -PRG of approximately 20,000-fold, almost doubling the selectivity ratio described above for UbV T66K/V70F -PRG (10,700-fold)."
35053210
sparser
"First, the authors identified multiple DUBs besides UCHL1 and UCHL3 that were associated with SARS-CoV-2 spike particle uptake in their siRNA screen."
36796097