IndraLab

Statements

Gallic acid inhibits NLRP3. 3 / 3
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"HSP90 is also essential for the activation of NLRP3 inflammasome, and geldanamycin (GA), a specific inhibitor of HSP90, blocks NLRP3 inflammasome activation and helps ameliorate NLRP3 inflammasome mediated diseases 35."
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"GA can inhibit the apoptosis and inflammation of HRECs under high glucose conditions by inhibiting the activity of the NOX4/NLRP3 pathway."
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"Additionally, gallic acid blocked NLRP3 inflammasome activation and inhibited the subsequent activation of caspase-1 and secretion of IL-1beta."
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