IndraLab

Statements

BAP1 activates PBRM1. 2 / 2

| 2

reach

"Interestingly, BAP1 loss reduced the protein levels of STAT2 and IRF9 independent of PBRM1 status, since RCC4 cells express no endogenous PBRM1 (XREF_FIG)."

30355451

➶

reach

"XREF_BIBR, XREF_BIBR Together these findings led us to propose a model where following inactivation of VHL and 3p loss, inactivation of the remaining copy of BAP1 caused aggressive ccRCC and inactivation of PBRM1, less aggressive ccRCC."

32206160

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

BAP1 activates PBRM1. 2 / 2

INDRA sources:

Databases

Reading