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Statements

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"These rescued recombinant MVs were designated IC-CAM H, IC-AIK-H, and IC-Tanabe H respectively ( Fig. 2 A )."
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"IC-CAM H, however, exhibited slower and less efficient growth than both IC-AIK H and IC-Tanabe H ( Fig. 2 B)."
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"IC-AIK H and IC-Tanabe H induced syncytia in both HeLa cells (data not shown) and NHDF as outlined in Fig. 2 C. However, the induction of syncytia by IC-CAM H was much less extensive in HeLa cells (da[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Accordingly, growth of IC-CAM H was significantly reduced in CD46-expressing HeLa cells and NHDF, and was slightly slower than that of IC323, IC-AIK H, and IC-Tanabe H in SLAM-expressing B95a cells."
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"IC-CAM H was found to grow in PHA-stimulated PBL to a similar degree as the other recombinant MVs studied, although the growth kinetics was slightly slower."
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"In marmoset B-lymphoid B95a cells, where SLAM is available for MV but not CD46 [48,49] , all of the recombinant MVs examined grew efficiently; however, the growth kinetics of IC-CAM H was always sligh[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"IC-CAM H did not grow efficiently in Mo-DC, even though both PHA-stimulated PBL and Mo-DC express CD46 and SLAM [50,51,53] ."
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"Although syncytia formation was observed in all recombinant MV-infected B95a cells, the spreading of syncytium was always slightly slower in the IC-CAM H-infected cells when compared to that in the ce[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In addition, growth of IC-CAM H was more reduced in CD46-expressing cells compared to SLAM-expressing cells, a result consistent with those described above, indicating that the ability of the CAM-70 H[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Thus in PHA-stimulated PBL, the CD46-dependent entry of IC-CAM H is likely to be much less efficient but the SLAM-dependent entry likely to be only slightly impaired."
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"This was in contrast to the impaired growth of IC-CAM H in these cells, suggesting that additional factors other than the H gene play important roles in the growth of the CAM-70 strain in the epitheli[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Similarly, CD46-dependent entry of IC-CAM H into Mo-DC also seems to be significantly less efficient."
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"These observations were consistent with those for the infection with IC-CAM H ( Fig. 2 B) and indicated that low fusion-inducing ability of the CAM-70 H protein was likely to slow growth kinetics of t[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In addition, we also assessed infection with recombinant MVs, IC-CAM H and IC-Tanabe H. We found that PHA-stimulated PBL and Mo-DC expressed both CD46 and SLAM, however the levels of their expression [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Although IC-CAM H grew efficiently, its growth kinetics was slightly slower than those of IC323 and IC-Tanabe H and its fusion induction was much less extensive ( Fig. 4 B and C)."
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"Similarly, IC-CAM H did not grow efficiently and syncytium formation was not observed ( Fig. 4 B and C)."
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"In addition, immunoblot analysis revealed that viral protein accumulation was below the limits of detection in the Mo-DC infected with the CAM-70 strain and IC-CAM H (data not shown)."
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