IndraLab

Statements

TUDCA inhibits NLRP3. 5 / 5
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"TUDCA treatment significantly suppressed the activation of NLRP3 and its downstream signaling in macrophages from both control and fatty livers after IR (Figure 4B)."
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"Curcumin, as well as TUDCA, attenuated NLRP3 and cleaved caspase-1 expression (Figs. 6 A & B), and as expected, reduced IL-1beta secretion."
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"Further, the ER stress TUDCA also suppressed NLRP3 activation in vitro, indicating that BHB is able to suppress NLRP3 inflammasome activation."
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"TUDCA could attenuate the NLRP3 inflammasome activation not only in vitro but also in vivo."
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"TUDCA Inhibits BCG-Infected THP-1 Macrophage NLRP3 Inflammasome Activity and Pyroptosis."
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