IndraLab

Statements


TP53 bound to ATG7 activates TP53. 1 / 1
| 1

reach
"We further showed that in Cnot3 -depleted hearts, Atg7 interacted with p53 and modulated p53 activity to induce the expression of genes encoding cell death promoting factors in cardiomyocytes, indicating that defects in deadenylation in the heart aberrantly activated Atg7 and p53 to promote cell death."