IndraLab

Statements


SLC5A3 activates KCNQ1. 3 / 3
| 3

reach
"SMIT1 augmented the activity of both KCNQ1 channels and KCNQ1-KCNE2 channels."

reach
"SMIT1 enhances KCNQ1 currents; KCNQ1 augments SMIT1 transport activity, but co-expression of both KCNE2 and KCNQ1 strongly inhibits SMIT1 activity."

reach
"This was demonstrated in a recent study in which KCNQ1 is coimmunoprecipitated with SMIT1 in the epithelium of the choroid plexus and that KCNQ1 activity is modulated by SMIT1 in a heterologous expression system [XREF_BIBR]."