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Isoprenaline activates KCNH2. 2 / 2

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"In addition, HERG is not activated by 8-Br-cAMP, consistent with the finding that isoproterenol does not increase IKr in cardiac myocytes (Sanguinetti et al., 1991)."

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"Controversially, Chen et al. also demonstrated that isoproterenol administration increased HERG abundance in HEK-293 cells co-transfected with HERG and beta-adrenergic receptor."

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Isoprenaline activates KCNH2. 2 / 2

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