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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP24 activates BAX. 4 / 5

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"USP24 induces apoptosis by stabilizing p300 and Bax."

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"In addition, USP24 also directed Bax protein stability to result in cell apoptosis."

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"USP24 knockdown decreases Bax protein stability in A549 and U2OS cells (XREF_FIG; XREF_SUPPLEMENTARY)."

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"The localization of Bax in cells expressing GFP-USP24 indicated that USP24 expression increased Bax 's mitochondrial localization, implying that USP24 induced cell apoptosis (XREF_FIG)."

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Statements

USP24 activates BAX. 4 / 5

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