IndraLab

Statements


4 | 3

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sparser
"USP2’s interaction with PD-L1 is a testament to its significance."

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"A recent study by Kuang et al ( xref ) reported that Thr288, Arg292 and Asp293 of USP2 bind to PD-L1 through the resolution of K48 link polyubiquitination at the PD-L1 lysine 270 site."

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"In colorectal cancer and prostate cancer cells, USP2 can directly interact with PD-L1 and promote the K48 deubiquitination of PD-L1."