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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP21 increases the amount of NFAT. 1 / 1

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"Mechanistically, they found that Usp16-mediated de-ubiquitination of calcineurin A, which is a calcium-activated phosphatase that dephosphorylates members of the nuclear factor of activated T cells (NFAT) family, leads to transcription of NFAT-targeted genes, which helps in the maintenance and proliferation of peripheral T cells [105]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...