A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

EGF binds EGFR, EREG, and AREG. 2 / 2
| 2
sparser
"Several ligands, such as EGF, amphiregulin, or epiregulin, bind specific extracellular domains of the EGFR, which activates an intracellular signalling cascade via different signalling pathways."
sparser
"Our results imply that SPHK1 may be the central controller of amplification loops of EGF, AREG and EREG-EGFR interactions that can contribute to cancer progression."