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USP2 activates Hypertrophy. 3 / 3
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"The above data suggested that USP2 overexpression alleviated Ang II-induced hypertrophy of cardiomyocytes.After the determination of calcium overload in vitro , it was found that Ang II induced increa[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Collectively, we hypothesized that Mycn possibly regulates USP2 transcription, which modulates JUP protein stability and the Akt/β-catenin signaling to affect cardiac hypertrophy progression."
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"Accordingly, our results revealed that USP2 overexpression improved cardiac functions, decreased the ratios of HW/BW and HW/TL, and reduced the degree of cardiac hypertrophy and fibrosis along with di[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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