IndraLab

Statements

eidos
"Findings from previous studies have suggested that chloroquine and hydroxychloroquine may inhibit the coronavirus through a series of steps ."
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"Results from a Chinese team indicated that HCQ inhibits coronavirus in vitro with EC50 of 0.72 mum and with a higher potency than CQ with EC50 of 5.47 mum [ 41 ] ."
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"Currently there is no accepted chemoprophylaxis but hydroxychloroquine ( HDQ ) is known to inhibit the coronavirus in vitro ."
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"After a questionable non-randomized open label clinical trial that reached the suspicious conclusion that hydroxychloroquine and azithromycin [ 115 ] together were effective in coronavirus elimination from nasopharyngeal swabs , a huge amount of other studies started to take place , despite the fact that hydroxychloroquine treatment had a low pretest likelihood of being effective at reducing disease morbidity and mortality ."
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eidos
"Previous studies suggested that CQ and HCQ may inhibit the coronavirus through a series of steps : ( i ) by changing the pH at the surface of the cell membrane and thus , inhibiting the fusion of the virus to the cell membrane , and ( ii ) by inhibiting nucleic acid replication , glycosylation of viral proteins , virus assembly , new virus particle transport , virus release and other processes to achieve its antiviral effects [ 49 ] ."
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