IndraLab

Statements

USP47 binds PNLIP. 7 / 7
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reach
"Next, the binding of USP47 and PTL was explored using cellular thermal shift assay (CETSA), a newly developed method to evaluate drug binding to target proteins in cells based on the biophysical princ[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34030041
reach
"To assess whether PTL binds to USP47, CETSA was firstly undertaken in HCT116 cell lysates."
34030041
reach
"Compared with DMSO treatment, PTL incubation resulted in an obvious thermostability of USP47 at different temperatures ( Fig. 3 E) and different doses ( Fig. 3 F), confirming the binding of PTL to USP[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34030041
sparser
"Next, the binding of USP47 and PTL was explored using cellular thermal shift assay (CETSA), a newly developed method to evaluate drug binding to target proteins in cells based on the biophysical princ[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34030041
sparser
"To assess whether PTL binds to USP47, CETSA was firstly undertaken in HCT116 cell lysates."
34030041
sparser
"Next, in order to investigate whether PTL interacts with USP47 in intact cells, HCT116 cells treated with PTL or DMSO were collected, lysed and heated."
34030041
sparser
"Compared with DMSO treatment, PTL incubation resulted in an obvious thermostability of USP47 at different temperatures ( Fig. 3 E) and different doses ( Fig. 3 F), confirming the binding of PTL to USP[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34030041