IndraLab

Statements

EGFR activates KCNA3. 3 / 3
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"This suggests that EGFR activation and down-regulation of Kv1.3 acts synergistically to promote NSC proliferation and migration."
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"The voltage-dependent potassium channel, Kv1.3 in HEK293 cells, is modulated by the epidermal growth factor receptor and the insulin receptor tyrosine kinases."
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"EGFR are linked to many potassium channels, i.e., Kv1.3 (15), Kv10.1 (16), Kv4.3 (17), and Kir2.3 (18), which are modulated by EGFR kinase via phosphorylation of tyrosine in their specific residues."
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