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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP7 deubiquitinates RB1. 4 / 4

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"In addition to stabilization of MDM2 by HAUSP, it might be possible that HAUSP reverses Rb ubiquitination by MDM2 in normal cells but is overwhelmed by abundant MDM2 in the case of tumor tissues or cancer cells."

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"HAUSP deubiquitinates Rb in vivo and in vitro, leading to an increased cell population in the G1 phase."

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"HAUSP deubiquitinates Rb."

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"Review"

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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USP7 deubiquitinates RB1. 4 / 4

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