IndraLab

Statements


USP7 deubiquitinates RB1. 4 / 4
1 | 3

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"In addition to stabilization of MDM2 by HAUSP, it might be possible that HAUSP reverses Rb ubiquitination by MDM2 in normal cells but is overwhelmed by abundant MDM2 in the case of tumor tissues or cancer cells."

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"HAUSP deubiquitinates Rb in vivo and in vitro, leading to an increased cell population in the G1 phase."

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"HAUSP deubiquitinates Rb."