IndraLab

Statements

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"91 Likewise, as a part of the PKA signaling pathway, cyclic adenosine monophosphate (cAMP) can also directly inhibit the NLRP3 inflammasome at Ser295 of its receptor."
31469975
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"CD39 expressing DCs converted extracellular ATP to ADP and AMP molecules, which were critical to down-regulate NLRP3 inflammasome and protect the host from experimental autoimmune encephalomyelitis (EAE)."
29033934
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"Of note, this previous study indicates that inhibition of AMP activated protein kinase (AMPK) can promote NLRP3 inflammasome activation by LPS and FFAs such as palmitate, but not by NLRP3 inflammasome activators used in our study such as ATP and nigericin 4."
27455510
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"Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition."
28933629