IndraLab

Statements

USP1 activates DNA Damage. 4 / 4
| 4
reach
"USP1 deubiquitylase stabilizes Survivin and promotes cell survival in response to endogenous replication stress and DNA damage."
37478161
reach
"Furthermore, the USP1 protein itself is reported to undergo rapid degradation in human cells after UV induced DNA damage."
18082605
reach
"In both Pt/PARPi-sensitive and -resistant cells, USP1/PARP1 combined blockade enhances replicative stress, DNA damage, and cell death."
39536107
reach
"Low levels of Usp1 in G1 allow an efficacious monoubiquitylation of PCNA in response to UV mediated DNA damage before DNA replication."
23159736