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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP1 activates DNA Damage. 2 / 2

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"Low levels of Usp1 in G1 allow an efficacious monoubiquitylation of PCNA in response to UV mediated DNA damage before DNA replication."

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"Furthermore, the USP1 protein itself is reported to undergo rapid degradation in human cells after UV induced DNA damage."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...