IndraLab
Statements
Carbamazepine inhibits FOS. 3 / 3
|
3
reach
"MK-801 or carbamazepine, which prevented hypoxia-ischemia-induced seizures, also prevented c-fos induction in the non ligated hemisphere while MK-801 was associated with increased c-fos induction in hippocampal neurones from the ligated side, as well as in glial like and ependymal cells."
reach
"Single intraperitoneal injection of carbamazepine (50 mg/kg), valproate (300 mg/kg) or intravenous injection of phenytoine (20 mg/kg) before noxious stimulation reduced the number of c-Fos immunoreactive neurons to 65-80% of control levels in superficial laminae and to 30-60% in deep laminae of the dorsal horn."
reach
"The high c-fos expression observed in the dentate gyrus is consistent with c-fos expression patterns observed in rats after strong, unilateral electrical stimulation of the hippocampus via an implanted electrode in animals treated with carbamazepine, which prevents seizures and also prevents bilateral c-fos staining upon unilateral stimulation."