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KCNH1-L704A inhibits calcium(2+). 1 / 1
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"Strikingly, although mutations L729A and L731A in the N-terminal extended stretch of BDC2 had a small effect on in vitro complex stability (XREF_FIG, red bar), the equivalent mutation in hEAG1 (L702A and L704A) caused a clear reduction of the channel 's Ca 2+ sensitivity, less than 10% current decrease during steady-state inhibition (XREF_FIG, red bar)."