IndraLab

Statements

USP18 activates CDKN1A. 4 / 4
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"Human immunodeficiency virus HIV-1 induced USP18 expression as a way to enhance HIV-1 infection in human monocytic leukemia cells, and USP18 promoted HIV replication by blocking the antiviral function[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In our recent studies, we demonstrate that HIV-1 infection induces USP18, which dramatically enhances HIV-1 replication by abrogating the antiviral function of p21."
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"We showed previously that USP18 contributes to HIV-1 replication by abrogating p21 antiviral function."
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"Here, we demonstrate a mechanism by which USP18 mediates p21 downregulation in myeloid cells."
31455647