IndraLab

Statements


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"Cisapride is a serotonin 5-HT4 receptor agonist that has been reported to block the hERG potassium channel."

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"This is the first study demonstrating that HERG potassium channels are blocked by the selective serotonin reuptake inhibitor fluoxetine."

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"Using whole-cell patch clamp recording of heterologous HERG mediated currents in transfected mammalian cells, we observed that the selective serotonin re-uptake inhibitor citalopram blocks HERG with an IC (50) of 3.97 microM."