IndraLab

Statements

ATM phosphorylates OTUD5. 2 / 2
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sparser
"This suggests the possibility that OTUD5 is directly phosphorylated by ATM to function as an amplifier of ATM-dependent DDR signaling in a potential positive-feedback circuit, resembling its role in mTOR signaling."
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reach
"This suggests the possibility that OTUD5 is directly phosphorylated by ATM to function as an amplifier of ATM-dependent DDR signaling in a potential positive-feedback circuit, resembling its role in mTOR signaling.In the context of DNA repair, OTUD5 has been suggested to promote NHEJ by counteracting the degradation of Ku80, a core NHEJ factor, in certain cell lines ."
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