IndraLab

Statements

USP7 deubiquitinates TP53BP1. 2 / 2
1 | 1
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"USP7 plays important roles in genomic stability and DNA damage response by deubiquitinating RNF168, BRCA1, 53BP1, Rad18, and many others [ 10–13 ]."
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"<span class="match term1">53BP1</span> depletion induces mitotic defects such as disorientation of spindle poles attributed to extra centrosomes or mispositioning of centrosomes, leading to phenotypes similar to those in <span class="match term0">USP7</span>-deficient cells."
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