IndraLab

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USP47 inhibits SMURF2. 4 / 4
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"SMURF2 is negatively regulated by USP47, and USP47 depletion sensitizes colon cancer cells to 5-FU-treatment-induced apoptosis."
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"Research has shown that ubiquitin-specific peptidase (USP47) negatively regulates Smurf2 to mediate colorectal cancer cell proliferation and tumor progression, but how USP47 regulates Smurf2 expressio[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, we show that SMURF2 functions as the E3 ubiquitin ligase for SATB1 and is negatively regulated by USP47."
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"Likewise, we reported that SMURF2 was negatively regulated by USP47 at the mRNA and protein levels."
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