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Adenosine 5'-monophosphate bound to NLRP3 inhibits NLRP3. 1 / 1

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"Soon afterwards, their data demonstrated that neurotransmitter dopamine (DA) could also inhibit NLRP3 inflammasome activation through dopamine D1 receptor (DRD1), suggesting DRD1 signaling could negatively regulate NLRP3 inflammasome via a second messenger cyclic adenosine monophosphate (cAMP), which binds to NLRP3 and promotes its ubiquitination and degradation."

30873162

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IndraLab

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Adenosine 5'-monophosphate bound to NLRP3 inhibits NLRP3. 1 / 1

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