IndraLab

Statements

SHH increases the amount of USP48. 3 / 3
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"In addition, we find that the Sonic Hedgehog (SHH) pathway induces USP48 expression through Gli1 mediated transcriptional activation, which forms thus a positive feedback loop to regulate Hh signaling."
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"Interestingly, the knockdown of Gli1 did not affect Shh-induced Usp31 expression."
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"To identify the signal mediating Shh-induced Usp31 overexpression, we first analyzed the promoter region of Usp31 ."
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