IndraLab

Statements


SHH increases the amount of USP48. 3 / 3
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sparser
"To identify the signal mediating Shh-induced Usp31 overexpression, we first analyzed the promoter region of Usp31 ."

reach
"In addition, we find that the Sonic Hedgehog (SHH) pathway induces USP48 expression through Gli1 mediated transcriptional activation, which forms thus a positive feedback loop to regulate Hh signaling."

sparser
"Interestingly, the knockdown of Gli1 did not affect Shh-induced Usp31 expression."