Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TLR4 binds HMGB1 and IL1B. 2 / 2

| 2

➶

sparser

"The results indicated that Nec-1 decreased the interaction between HMGB1 and TLR4 induced by IL-1β."

30542285

➶

sparser

"Although HMGB1 has been shown to stimulate pro-inflammatory cytokine production xref , xref , xref , it is unlikely that HMGB1 interacts with TLR4 to promote IL-1β production and cell death in our system."

22563435

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...