IndraLab

Statements

NFKBIA binds USP39. 4 / 4
2 | 2
sparser
"IκBα has been shown to be a negative regulator in the inflammatory response to NF-κB, and USP39 binds to IκBα preventing IκBα degradation by removing the ubiquitin chain of IκBα at Lys48-linked ubiquitination to inhibit inflammation occurrence ( xref )."
40672756
sparser
"In the inflammatory response, USP39 interacts with IκBα, stabilizing basal levels of IκBα by reducing K48-linked polyubiquitination on IκBα."
40990019
biogrid
No evidence text available
36651806
biogrid
No evidence text available
36651806