IndraLab

Statements

KCNMA1 inhibits fAHP. 2 / 2
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"BK channel inactivation is associated with broader action potential half-width and reduced fAHP amplitude (Faber and Sah, 2003; Guo et al., 2012; Sun et al., 2015)."
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"Acute application of the BK channel selective antagonist iberiotoxin (IbTx, at 100 nM) significantly decreased fAHP without affecting mAHP in NAc MSNs in control slices (fAHP, t (4) = 3.53, p < 0.05; mAHP, t (4) = 1.08, p = 0.34; XREF_FIG), indicating that the defined fAHP in NAc MSNs was primarily mediated by BK channels."
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