IndraLab

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OTUB1 leads to the deubiquitination of HIF1. 3 / 3

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"Moreover, ectopic expression of OTUB1 in H1299 cells suppressed ubiquitination of endogenous HIF-1α (Fig. 5L)."

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"By contrast, knockout of OTUB1 in H1299 (OTUB1 ) enhanced ubiquitination of HIF-1α (Fig. 5M)."

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"As expected, overexpression of OTUB1 reduced K48 linkage-specific ubiquitination of HIF-1α (Fig. 6G)."

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IndraLab

Statements

OTUB1 leads to the deubiquitination of HIF1. 3 / 3

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