IndraLab

Statements

USP8 decreases the amount of MET. 2 / 3

1 | 1

reach

"Ubiquitinated LRIG1 recruits c-Met to lysosomes for degradation; reduction in LRIG1 ubiquitination by USP8 depletion or inactivation thus enables c-Met levels and functionality to be maintained."

29543760

➶

signor

"Degradation of acutely stimulated receptor tyrosine kinases, epidermal growth factor receptor and Met, is strongly inhibited in UBPY knockdown cells suggesting that UBPY function is essential for growth factor receptor down-regulation."

16520378

INDRA sources:

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IndraLab

Statements

USP8 decreases the amount of MET. 2 / 3

INDRA sources:

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