
IndraLab
Statements
KCNH1 activates Neoplasm Metastasis. 3 / 3
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3
reach
"For example, inhibition of the potassium channels, KCNK9 [XREF_BIBR], Kv10.1 [XREF_BIBR], hEag1 [XREF_BIBR], and HERG1 [XREF_BIBR] inhibited tumor metastasis, as did inhibition of the sodium channels, Na (v1.4) [XREF_BIBR] and Na (v) 1.5 [XREF_BIBR] and the sodium proton exchanger, NHE1 [XREF_BIBR, XREF_BIBR]."
reach
"Using multiple Drosophila brain tumor models induced by oncogene overexpression or loss of tumor suppressors to complement our study of mice with xenografted human MB cells, we show that the functions of EAG2 and Eag channel to promote malignant growth and metastasis are evolutionarily conserved (XREF_FIG)."