IndraLab

Statements

CYLD activates Mice. 3 / 3
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"- Cyld knockout impairs amygdala-dependent tone-cued fear memory in mice.- Cyld mice display aberrant neuronal activation in BLA in response to tone-cued fear test.- Cyld mice show decreased excitability of BLA principal neurons.- CYLD is critical for both excitatory and inhibitory synaptic neurotransmission in mouse BLA."
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"Our TFC test revealed that Cyld knockout impairs fear memory in mice."
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"Taken together, these results suggest that CYLD deficiency disrupts the neuronal activity and synaptic transmission in the BLA of mice which may contribute to the impaired fear memory observed in Cyld -/- mice."
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