IndraLab

Statements


CYLD activates Mice. 5 / 5
| 5

reach
"In assessments of motor performance by the pole test, CYLD KD also rescued motor deficits in the conditional parkin KD mice evident from the decreased time to turn and time to reach the base (fig."

reach
"Taken together, these results suggest that CYLD deficiency disrupts the neuronal activity and synaptic transmission in the BLA of mice which may contribute to the impaired fear memory observed in Cyld -/- mice."

reach
"- Cyld knockout impairs amygdala-dependent tone-cued fear memory in mice.- Cyld mice display aberrant neuronal activation in BLA in response to tone-cued fear test.- Cyld mice show decreased excitability of BLA principal neurons.- CYLD is critical for both excitatory and inhibitory synaptic neurotransmission in mouse BLA."

reach
"Our TFC test revealed that Cyld knockout impairs fear memory in mice."

reach
"It has been demonstrated that CYLD deficiency disrupts neuronal activity and synaptic transmission in the BLA of mice, potentially leading to impaired fear memory."