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USP11 deubiquitinates ubiquitinated SPRTN. 2 / 2

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"The monoubiquitinated SPRTN is deubiquitinated by USP11, and the unmodified SPRTN only is localized to chromatin upon DNA damage by DPC-inducing agents (7, 57)."

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"We observed that monoubiquitinated SPRTN is deubiquitinated by USP11 FL, but not C318S deubiquitinase inactive mutant (XREF_FIG C and Fig.S2A)."

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USP11 deubiquitinates ubiquitinated SPRTN. 2 / 2

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