IndraLab

Statements

OTUB1 increases the amount of HK2. 4 / 4
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"For example, in breast cancer studies, OTUB1 enhances the transcriptional activity of MYC and induces the expression of HK2, thus promoting aerobic glycolysis [13]."
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"In breast cancer, OTUB1 stabilized MYC and increased HK2 expression which promoted aerobic glycolysis eventually [17]."
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"Han et al.66 found that the deubiquitinase OTUB1 stabilized MYC and induced HK2 expression, which leads to the promotion of aerobic glycolysis and breast tumorigenesis."
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"In breast cancer, OTUB1 promotes the protein stability of MYC through deubiquitination and mediates HK2 expression to increase aerobic glycolysis (Han et al., 2022)."
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