IndraLab

Statements

STAMBPL1 increases the amount of HIF1A. 5 / 5
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"We demonstrated that STAMBPL1 increased HIF1A transcription in a non-enzymatic manner, thereby activating the HIF1alpha/VEGFA signaling pathway to facilitate triple-negative breast cancer angiogenesis."
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"STAMBPL1 promotes HIF1A transcription and activates the HIF1alpha/VEGFA axis."
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"Data showed that STAMBPL1 overexpression increased the transcription of HIF1A (Figure 4E, Figure 4—figure supplement 1E) and VEGFA (Figure 2E, G)."
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"These findings suggested that STAMBPL1 activated the HIF1α/VEGFA axis through enhancing the transcription of HIF1A."
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"By silencing the STAMBPL1 gene in HCC1806 cells subjected to 10 hr of hypoxia, we performed RNA-seq analysis to investigate the mechanism by which STAMBPL1 promotes HIF1A transcription."
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