IndraLab

Statements


Mgt inhibits KCNA2. 2 / 2
| 2

sparser
"However, both Kv1.2 and Kv1.3 were inhibited by MgTx at this concentration ( xref , Mann-Whitney U, non-parametric paired t -test, p = 0.0013 for Kv1.2, n = 6-7; p = 0.0001 for Kv1.3, n = 16-18)."

sparser
"MgTx was considered a selective inhibitor of the Kv1.3 channels but it was demonstrated that MgTx inhibits Kv1.2 and Kv1.3 channels with low picomolar affinities (Kd = 11.7 pM for Kv1.3 and Kd = 6.4 pM for Kv1.2) [ xref ]."