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USP33 activates ISG75. 2 / 2

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reach

"Two T. brucei orthologues of human deubiquitinases Usp7 and Vdu1 designated TbUsp7 and TbVdu1 were confirmed to be expressed in the parasite, and their knockdown increased the turnover of ISG75 and ISG65 (Zoltner et al., 2015)."

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reach

"ISG75 stability is regulated by ubiquitylation [XREF_BIBR] and evidence that trypanosome Usp7 and Vdu1 modulate ISG75 turnover is consistent with this model [XREF_BIBR]."

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USP33 activates ISG75. 2 / 2

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