IndraLab

Statements

RNF41 activates USP8. 3 / 3
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"Nrdp1 activates NRG-1beta-induced HER3 degradation [XREF_BIBR] and USP8 prevents Nrdp1 auto-ubiquitination [XREF_BIBR], with a strong correlation between USP8 expression and Nrdp1 stabilization [XREF_BIBR]."
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"This result suggests that USP8 increases the expression of Nrdp1 which is associated with the potent downregulation of TLR4 signaling activity in LPS-induced mice.To compare the effect of USP8 on cogn[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Since Nrdp1 targets USP8 for ubiquitylation, we speculated that overexpression of Nrdp1 could enhance protein ubiquitylation and USP8 degradation in PC12 cells."
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