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RNF41 activates USP8. 2 / 2

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"Since Nrdp1 targets USP8 for ubiquitylation, we speculated that overexpression of Nrdp1 could enhance protein ubiquitylation and USP8 degradation in PC12 cells."

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"Nrdp1 activates NRG-1beta-induced HER3 degradation [XREF_BIBR] and USP8 prevents Nrdp1 auto-ubiquitination [XREF_BIBR], with a strong correlation between USP8 expression and Nrdp1 stabilization [XREF_BIBR]."

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RNF41 activates USP8. 2 / 2

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