IndraLab

Statements


USP10 inhibits SIRT6. 3 / 15
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"Accordingly, inactivation of USP10 reduced Sirt6 abundance and stability and diminished Sirt6 induced downstream signaling in cardiomyocytes."

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"Moreover, USP10 attenuates sepsis-induced oxidative stress in renal tissues by increasing SIRT6 stability and activating the NRF2 /ARE signaling pathway."

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"Additionally, the ubiquitin-specific peptidase 10 ( USP10 ) inhibits hepatic steatosis, insulin resistance, and inflammation via sirt6 ( Luo et al., 2018 )."