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EMMAA Bob with Bioagents

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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP14 inhibits Cell Survival. 5 / 5

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"Similarly , UbVs were generated with high affinity for USP14 , which inhibited Ub signaling and cell survival in yeast [ 106 ] ."

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"Interference of USP14 suppressed MCL cell viability, potentiated cell cycle arrest, apoptosis, and ibrutinib sensitivity."

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"USP14 and UCHL5 short interfering RNA knockdown decreases MM cell viability."

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"Knock-down of USP14 in multiple myeloma cells induces loss of cell viability."

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"Similarly, UbVs were generated with high affinity for USP14, which inhibited Ub signaling and cell survival in yeast [XREF_BIBR]."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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