IndraLab

Statements

KCNH2 activates cell adhesion. 4 / 5
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"Finally, the beta1 integrin subunit, K V 11.1 and NHE1 co-immunoprecipitated in colorectal cancer cells seeded onto Collagen I, suggesting the formation of a macromolecular complex following integrin-mediated adhesion."
32587517
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"HERG K+ channels activation during beta (1) integrin mediated adhesion to fibronectin induces an up-regulation of alpha (v) beta (3) integrin in the preosteoclastic leukemia cell line FLG 29.1."
11080495
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"Moreover, K v 3.3 may also be involved in the cell adhesion process, similar to the function of hERG potassium channels [XREF_BIBR], even if the effect is in the opposite direction; the hERG potassium channels enhance cell adhesion, whereas K v 3.3 inhibits cell adhesion."
26849432
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"We have recently shown that hERG1 is physically linked to beta1 integrins and thereby modulate adhesion dependent signaling (Cherubini et al, 2005)."
16175187