IndraLab

Statements

PNLIP inhibits USP47. 6 / 6
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"In this study we found PTL effectively inhibited USP47 and CRC, which is also an inhibitor of USP7 we previously reported [ 22 ]."
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"In this study we found PTL effectively inhibited USP47 and CRC, which is also an inhibitor of USP7 we previously reported [ 22 ]."
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"As shown in Fig. 3 A–B, PTL inhibited USP47 activity in dose- and time-dependent manner."
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"In summary, PTL inhibited USP47 and improved the thermostability of USP47, indicating PTL was a novel USP47 inhibitor.Next, we explored whether the USP47 inhibitor PTL effectively inhibited CCSCs."
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"These results indicated USP7 might not regulate CCSCs, and PTL modulates CCSCs preferentially by antagonizing USP47.In this study, we demonstrated that USP47 regulates CCSCs, and as an inhibitor of US[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34030041
sparser
"In summary, PTL inhibited USP47 and improved the thermostability of USP47, indicating PTL was a novel USP47 inhibitor."
34030041