IndraLab

Statements


USP19 inhibits ISRE. 2 / 2
| 2

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"As shown in Fig. 8a, USP19 markedly inhibited ISRE activation mediated by wild-type and all of the tested mutants of TRIF, with the exception of TRIF(K523R)."

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"Reporter assays indicated that USP19 inhibited ISRE activation mediated by overexpression of TRIF but not TBK1 or IRF3 (Fig. 4a)."