IndraLab

Statements

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"Therefore, EGCG can inhibit the MAPK/ERK and PI3K/Akt signaling pathways, as well as the activation of NFkB."
32092951
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"The present study also showed that dietary supplementation with EGCG decreased the inflammatory transcripts of nf-kb and il-6 in Chinese rice field eels."
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"In mice, EGCG has been shown to protect against ischemia reperfusion injury in a NRF2-dependent manner (Han et al., 2014) and has also been shown to inhibit NFkB activity, reduce Aβ fibrilization, and improve memory in Aβ exposed animals (Lee et al., 2009b)."
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"The anti-inflammatory activities of EGCG are well demonstrated in in vitro and in vivo models, accompanied by increased Nrf2 signaling and inhibited NFkB pathway through its antioxidant activity [112,113,114]."
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"EGCG also blocks LPS induction of nitric oxide synthase in mouse macrophages, by down-regulating the LPS induced activity of the transcription factor NF-KB [8]."
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