IndraLab

Statements


USP24 decreases the amount of E2F4. 4 / 5
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"However, the overexpression of E2F4 following USP24 knockdown elevates E2F1 mRNA levels and partially reduces the G1-S transition."

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"USP24 inhibits the G1-S transition by increasing the E2F4 level."

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"Knockdown of USP24 decreased the E2F4, p130 and TFDP1 levels, which form a complex to regulate the G1-S transition, but did not alter the E2F4 and TDFP1 mRNA levels (XREF_FIG; XREF_SUPPLEMENTARY)."

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"Targeting USP24 decreases E2F4 and TRAF6 levels to induce autophagy in interphase and mitotic cancer cells."