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EIF3F inhibits cell growth. 15 / 19
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"The same group found that eIF3f overexpression in cancer cells negatively regulates cell growth by affecting the translation efficiency and the activation of apoptosis."
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"The data also suggest that eIF3f inhibits cancer cell growth and induces apoptosis by blocking the function of sCLU, thereby suppressing the inactivation of p53 and Bax as well as the Akt and ERK pathways."
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"Endogenous eIF3f silencing by antisense RNA or siRNA inhibits cell growth and induces apoptosis in A549 cancer cells."
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"XREF_BIBR, XREF_BIBR, XREF_BIBR Advances in the understanding of the molecular mechanism behind cellular carcinogenesis have shown that ectopic expression of eIF3f by transient gene transfection inhibits translation, cellular growth and proliferation and induces apoptosis."
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"We also previously showed that ectopic expression of eIF3f inhibited cell growth and induced apoptosis xref ."
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"Ectopic overexpression of each eIF3 subunit (with the exception of eIF3m) in NIH 3T3 cells revealed that subunits eIF3a, eIF3b, eIF3c, eIF3h, and eIF3i stimulated global protein synthesis, accelerated[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Ectopic expression of eIF3e and eIF3f subunits in stably transfected NIH3T3 fibroblasts also inhibits cell growth and proliferation [XREF_BIBR]."
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"We also previously showed that ectopic expression of eIF3f inhibited cell growth and induced apoptosis XREF_BIBR."
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"It is demonstrated that the enforced expression of eIF3f inhibits translation, cell growth, cell proliferation and induces apoptosis in melanoma and pancreatic cancer cells, while knockdown of eIF3f i[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Increased expression of eIF3f reduces cellular growth by inducing apoptosis in melanoma and pancreatic cancer cells [XREF_BIBR - XREF_BIBR]."
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"The overexpression of eIF3f inhibits cancer cell growth and induces apoptosis."
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"We then examined whether the inhibited cell growth induced by eIF3f overexpression was associated with increased apoptosis using flow cytometry."
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"Therefore, eIF3f inhibits cancer cell growth and induces apoptosis by inhibiting sCLU function."
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"Moreover, increased eIF3f inhibits translation and cell growth and induces apoptosis in melanoma and pancreatic cancer cells [XREF_BIBR]."
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"In addition, eIF3f reduces cell growth and increases apoptosis significantly in HeLa and BxPc-3 cells."
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